Mr Brian Leedman
Non-Executive Director

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Non-Executive Director
Mr Leedman is a marketing and investor relations professional with over 15 years’ experience in the biotechnology industry. Mr Leedman is the founder of ResApp Diagnostics Pty Ltd which was acquired by Narhex Life Sciences Limited to form ResApp Health Limited where Mr Leedman is the Executive Director of Corporate Affairs. ResApp Health is currently under a Scheme of Arrangement to be acquired by Pfizer (Aust) Limited.
Mr Leedman is an experienced public company director having formerly been the Chairman of Neurotech International Limited, Nutritional Growth Solutions Limited, Neuroscientific Biopharmaceuticals Limited and was a Director of Alcidion Corporation Limited.
Prior to ResApp, Mr Leedman co-founded OncoSil Medical Limited and Biolife Science (QLD) Limited (acquired by Imugene Limited). Mr Leedman previously served for ten years as Vice President, Investor Relations for pSivida Corp. Limited, which was listed on the ASX, Frankfurt and NASDAQ. He was formerly the WA Chairman of AusBiotech, the association of biotechnology companies in Australia. Mr Leedman holds a Bachelor of Economics and a Master of Business Administration from the University of Western Australia.
Chief Medical Officer
Dr Jon Bell trained in surgery and clinical radiology before completing higher sub-specialty training in Interventional Radiology. He is an internationally recognised expert in Interventional Oncology and his primary research interest is in liver directed brachytherapy.
Jon is a member of the Interventional Procedures Committee at the National Institute for Health and Care Excellence and former chair of the Patient Safety and Quality Committee of the British Society of Interventional Radiology. He was awarded Fellowship of the Cardiovascular and Interventional Radiological Society of Europe in 2019.
Chief Executive Officer
and Managing Director
Nigel Lange is the Chief Executive Officer, Managing Director and President of EMEA for OncoSil Medical. Nigel has over 35 years’ experience in the medical device and pharmaceutical industries, with over 20 years’ experience in brachytherapy. Nigel is also a specialist in corporate turnaround.
Nigel assumed the role of CEO and MD for OncoSil Medical in January 2021. Prior to his role as CEO, he was appointed President of EMEA in May 2020 with responsibility for EMEA business development and commercialisation and he continues to serve in this role.
Previously, Nigel served as Chief Executive Officer at Sirtex Medical where he was responsible for the global business development and engineered a restructure of the company which resulted in the realisation of a cost saving of $45 million.
In his 16-year career at Sirtex, Nigel has held several executive roles across different regions globally while focusing on business leadership, corporate development, strategic licensing agreements with third parties, mergers and acquisitions and sales management. Nigel established the European division of Sirtex, where the technology had become a prominent treatment for liver cancer in over 300 centres across EMEA and achieved market penetration in all major EU markets.
Prior to Sirtex, Nigel started his extensive career in brachytherapy at MDS Nordion in 1999 in the targeted therapies division and has continued to grow his expertise over the following years.
Nigel received his Bachelor of Arts from York University, Ontario in 1980 and followed on with a Bachelor of Commerce from the University of Windsor, Ontario where he graduated in 1984.
Non-Executive Chairman
Mr Buttula has had extensive experience and success in investment research, funds management and information technology and has held directorships in a number of public companies. Mr Buttula’s executive experience includes co-founder and CEO and Managing Director of IWL Limited, an online financial services company that listed on the ASX in 1999. The company grew from a market capitalisation of $48 million at listing before a takeover in 2007 by Commonwealth Bank of Australia for $373 million. Mr Buttula also founded and was Managing Director of Investors Mutual, prior to which he was a co-founder and director of Lonsdale Securities Limited.
Following his completion of executive duties, Mr Buttula was Non-Executive Chairman of platform and stockbroking provider Investor first Limited and led the acquisition of HUB24 Limited (ASX: HUB). More recently, he served on the Board as a non-executive director and Head of Audit & Risk at Imugene Limited (ASX: IMU) between 2014 and 2016 and currently is the Non-Executive Chairman of Rhythm Biosciences (ASX:RHY)
Global Head of Clinical Affairs
Henk Tissing is the Director of Global Clinical Affairs at OncoSil Medical. He is responsible for leading the clinical research program on novel provide global clinical evidence for the company.
Henk comes with over 25 years’ experience in the medical device and pharmaceutical industry specializing in the development and management of national and international clinical studies. More specifically, Henk has held senior leadership positions in the development of clinical programs for brachytherapy over the past 10 years.
Prior to joining OncoSil, Henk held the position of Vice President, Clinical Development Interventional Oncology for BTG (Now acquired by Boston Scientific) responsible for the clinical development program for SIRT, Bland/Drug-eluting Beads and Cryoablation products and prior to that, was the Director of Clinical Affairs, EMEA for SIRTEX Medical, responsible for the planning and execution of the Clinical Research Program in the EMEA region.
Henk graduated with his degree in Biomedical Sciences at the Leiden State University, faculty of Medicine, Leiden, The Netherlands in 1991.
Global Head of Medical Affairs
David Turner is the Global Head of Medical Affairs for OncoSil Medical. He is responsible for bridging relationships between the oncology community and the research and commercial sides of the business, as well as analysis of clinical studies, and development of the publications plan.
An immunologist by training, David brings over 40 years’ experience in healthcare, working both within the pharmaceutical, medical device, diagnostics, and health technology industries, as well as at a senior level in healthcare consulting. He has spent the past 30 years in scientific affairs and marketing with a significant emphasis on oncology.
David has over 25 years at board and senior executive level, most recently as Global Head of Marketing for Sirtex Medical Limited. He previously contributed substantially to the growth of two international healthcare marketing communication consultancies from start up to the largest practices in their sectors, as well as the leading oncology patient information and chemotherapy prescribing system. David also directed a patient advocacy campaign which successfully lobbied the UK government to substantially increase funding for oncology drugs and services in the NHS.
VP Regulatory Affairs and Quality
Nicole Wilson is the Vice President of Regulatory Affairs and Quality at OncoSil Medical, with over 15 years’ experience in industry. In this role, Nicole oversees global strategic alignment to support the business growth through the overall development, implementation, maintenance, compliance, and execution of strategies ensuring that approaches are innovative, industry-leading, and meeting the needs of customers and the business from a Quality and Regulatory perspective.
Prior to joining OncoSil, Nicole was a Global Regulatory Affairs Manager at Sirtex Medical, focusing on preparation and maintenance of international product registrations for their brachytherapy device.
Nicole has a science degree majoring in physics.
Chief Financial Officer
Karl Pechmann is the Chief Financial Officer and Company Secretary at OncoSil Medical responsible for leading the global finance organization and key supporting functions including Controller, Tax, Internal Audit, Investor Relations, Corporate Strategy and Business Development.
Karl joined OncoSil in March 2020 from Kyckr Limited where he served as Chief Financial Officer and Company Secretary for over 3 years. Prior to Kyckr, he held senior finance roles at both ASX-listed and multi-national organisations specializing in capital raising, investor relations, operating efficiencies, and financial management.
Karl earned his degree in Finance in 2004 at the University of Technology in Sydney and gained his Diploma of Chartered Accounting in 2005 and Diploma in Applied Corporate Governance in 2011.
Chief Executive Officer
and Managing Director
Nigel Lange is the Chief Executive Officer, Managing Director and President of EMEA for OncoSil Medical. Nigel has over 35 years’ experience in the medical device and pharmaceutical industries, with over 20 years’ experience in brachytherapy. Nigel is also a specialist in corporate turnaround.
Nigel assumed the role of CEO and MD for OncoSil Medical in January 2021. Prior to his role as CEO, he was appointed President of EMEA in May 2020 with responsibility for EMEA business development and commercialisation and he continues to serve in this role.
Previously, Nigel served as Chief Executive Officer at Sirtex Medical where he was responsible for the global business development and engineered a restructure of the company which resulted in the realisation of a cost saving of $45 million.
In his 16-year career at Sirtex, Nigel has held several executive roles across different regions globally while focusing on business leadership, corporate development, strategic licensing agreements with third parties, mergers and acquisitions and sales management. Nigel established the European division of Sirtex, where the technology had become a prominent treatment for liver cancer in over 300 centres across EMEA and achieved market penetration in all major EU markets.
Prior to Sirtex, Nigel started his extensive career in brachytherapy at MDS Nordion in 1999 in the targeted therapies division and has continued to grow his expertise over the following years.
Nigel received his Bachelor of Arts from York University, Ontario in 1980 and followed on with a Bachelor of Commerce from the University of Windsor, Ontario where he graduated in 1984.
Non-Executive Director
Professor Sharma is an international authority on the translation of radiobiology from the laboratory to the clinic and on the multi-modality treatment of cancer with precision radiotherapy. He is currently Vice President Clinical Affairs at Varian, a Siemens Healthineers company.
Professor Sharma is also a honorary consultant in clinical oncology at University College London Hospitals, where he has a clinical practice in radiotherapy and chemotherapy. He has led a research team at University College London that translated discoveries in radiotherapy research to clinical trials to improve treatment for patients with cancer.
Professor Sharma was previously an associate professor at the University of Oxford, and a honorary consultant in clinical oncology at Oxford University Hospitals. He has over 200 publications in peer-reviewed scientific journals, including Lancet and Nature journals.
Professor Sharma has previously been the chair of radiation oncology at University College London and a scientific group leader at the UCL Cancer Institute and he was a former chair of working groups for NHS/NICE evaluations of novel radiotherapy treatments.
He graduated in medicine from the University of Cambridge, United Kingdom. He trained in general internal medicine, medical oncology and radiation oncology and completed a Phd on DNA damage repair.
Non-Executive Director
Dr Cross is a highly regarded pharmaceutical executive with over 30 years’ experience including corporate and industry leadership roles directly influencing healthcare policy and government legislation in Australia and global business management, marketing and sales roles.
From 2013 to 2015, Dr Cross was Chairman of Medicines Australia, the country’s peak body representing the research based pharmaceutical industry in Australia. Prior to leading Medicines Australia, from 2010 to 2013 Dr Cross was Chairman of both the Generics Medicine Industry Association and Pharmaceutical Industry Council. During this time, Dr Cross was also Managing Director of Alphapharm in Australia and New Zealand, with responsibility for 750 employees and sales of over US $500m per annum.
From 2003 to 2008, Dr Cross was Country Head and Managing Director of Novartis Australia and New Zealand, and Head of Global Marketing and Sales Capabilities from 2001 to 2003, based in Switzerland.
Head of Manufacturing and Operations, RSO
David James is the Head of Manufacturing and Operations as well as the Radiation Safety Officer at OncoSil Medical. He is responsible for the performance and integration of all aspects of the company’s operations including Manufacturing, Supply Chain, Supply Management, Customer Service, Product R&D, Operational Excellence and Operations Quality. David joined OncoSil Medical in 2015 and comes with over 25 years’ experience in this field.
Prior to joining OncoSil, David ran his own consulting firm specialising in the medical device, veterinary medicines and pharmaceutical industry specializing in production, supply chain, production site set-up, product formulation and pharmaceutical processing skills.
Previously, David was the Global Operations Manager at Sirtex Medical where he was responsible for managing the global operations team which includes production, supply chain, customer service and engineering. He also had the responsibility for the design, construction, and commissioning of Sirtex’s first in-house manufacturing plant in Wilmington DC, USA.
David has a master’s in Business and Technology from the University of New South Wales, and a Bachelor of Science from the University of Newcastle. David is a Chartered Chemist with the Royal Australian Chemical Institute.
Non-Executive Director
B.SC (Hons) and Ph.D. (Aberdeen) FAICD
Dr Cross is a highly regarded pharmaceutical executive with over 30 years’ experience including corporate and industry leadership roles directly influencing healthcare policy and government legislation in Australia and global business management, marketing and sales roles.
From 2013 to 2015, Dr Cross was Chairman of Medicines Australia, the country’s peak body representing the research based pharmaceutical industry in Australia. Prior to leading Medicines Australia, from 2010 to 2013 Dr Cross was Chairman of both the Generics Medicine Industry Association and Pharmaceutical Industry Council. During this time, Dr Cross was also Managing Director of Alphapharm in Australia and New Zealand, with responsibility for 750 employees and sales of over US $500m per annum.
From 2003 to 2008, Dr Cross was Country Head and Managing Director of Novartis Australia and New Zealand, and Head of Global Marketing and Sales Capabilities from 2001 to 2003, based in Switzerland.
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